We aim to uncover the structure and function of proteins to explore their diverse applications. Our research is guided by the following key objectives:
Aim 1: Stress Response and Membrane Proteins
We investigate the critical roles of membrane proteins in stress perception, signal transduction, and adaptation mechanisms. Our current focus is on plant membrane proteins that mediate responses to salinity stress, striving to uncover their molecular mechanisms and contributions to stress tolerance.
Aim 2: Recombinant Membrane Protein Expression, Purification, and Characterization
Membrane protein purification is a complex challenge due to their inherent hydrophobicity and dynamic nature. We develop and optimize protocols for recombinant expression, purification, and functional characterization of membrane proteins to enable deeper insights into their roles.
Aim 3: Protein Engineering
We apply sequence- and structure-guided protein engineering approaches to enhance or suppress specific protein functions, enabling tailored solutions for various biological and biotechnological applications.
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Institution Seed Grant (Thapar Institute of Engineering and Technology) sanctioned amount 6.6 lakhs, (2021 - 2023), PI
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Indo-Russian Joint Research Call (Department of Science and Technology, Govt. of India) sanctioned amount 87.29 lakhs, (2023 - 2026), CoPI
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Startup Research Grant (Science and Engineering Research Board) sanctioned amount 28.23 lakhs, (2022 - 2024), PI