

Our research is inspired by the remarkable correlation between the structure and function of proteins. We currently focus on three core research areas:
Aim 1: Protein Structure-Function Relationship and Protein Engineering
We apply sequence- and structure-guided protein engineering approaches to enhance or suppress specific protein functions, enabling tailored solutions for a range of biological and biotechnological applications.
Aim 2: Membrane Proteins in Stress Response
We investigate the critical roles of membrane proteins in stress perception, signal transduction, and adaptation mechanisms. Our current focus is on plant membrane proteins that mediate responses to salinity stress, aiming to uncover their molecular mechanisms and contributions to stress tolerance.
Aim 3: Recombinant Membrane Protein Expression, Purification, and Characterization
Membrane protein purification remains a complex challenge due to their inherent hydrophobicity and dynamic nature. We develop and optimize protocols for the recombinant expression, purification, and functional characterization of membrane proteins to gain deeper insight into their biological roles.
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Institution Seed Grant (Thapar Institute of Engineering and Technology) sanctioned amount 6.6 lakhs, (2021 - 2023), PI
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Indo-Russian Joint Research Call (Department of Science and Technology, Govt. of India) sanctioned amount 87.29 lakhs, (2023 - 2026), CoPI
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Startup Research Grant (Science and Engineering Research Board) sanctioned amount 28.23 lakhs, (2022 - 2024), PI
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Biological Science catagory (Department of Biotechnology, Govt. of India) sanctioned amount 62.83 lakhs (2025 - 2028), CoPI
Our Lab is supported by




